Dr, Department of Oral Medicine and Radiology, Indira Gandhi Institute of Dental Sciences, Pondicherry, India
Comparison of Clinical and Histopathological Behavior of Oral Leukoplakia Before and After Treatment with 1% Topical Clotrimazole
- An Observational Study
Author(s): Kayal Vizhi*
Background: The Etiological role of Candida albicans in malignant transformation of oral leukoplakia is much debated in the recent times.
Aim and objectives: To compare the clinical and histopathological behavior of oral leukoplakia before and after antifungal therapy with 1% topical clotrimazole. To assess the candida colony count in saliva and correlation between salivary candidal colonies count in patients with oral leukoplakia before and after treatment with antifungal 1% topical clotrimazole therapy.
Methods: Clinical behavior of 50 cases of oral leukoplakia was assessed and histopathological confirmed as not any other lesion. Unstimulated whole saliva sample collection for estimating candida colony count and exfoliative cytology of the lesion were performed with cytobrush to evaluate .. Read More»