Department of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
Publications
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Reviews
Potential Disadvantages Associated with Treatment of ActiveTuberculosis Using Fixed-Dose Combination: A Review of Literature
Author(s): Sadia Iftikhar and Muhammad Rehan Sarwar*
Abstract
Background and Objectives: Prevalence of Tuberculosis (TB) is quite high in various regions of the world. Fixed-dose combination (FDC) is highly recommended in various cases like TB, diabetes mellitus, hypertension, etc. Various studies are conducted to assess safety and efficacy of FDC. Likewise, prime focus of present review is to evaluate the potential disadvantages of FDC and compare it with single formulation (SF). Methods: We used a number of electronic databases to identify the relevant published studies which demonstrated the disadvantages regarding fixed dose combination for tuberculosis. Of 204 articles found initially, 143 were selected for additional review. Subsequently, 72 articles were finally selected. Results and Conclusions: Being a disease of poor, several advantages like cost-effectiveness, reduction in pill burden and logistical advantages, etc. can be achieved wi..
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