Department of Clinical Pharmacist, University of Kuwait, Salmiya, Kuwait

Publications

  • Commentary   
    Evaluation of Hydrophobic Coated Buoyant Core as Floating Drug Delivery System
    Author(s): Maxwell Christopher Manley*

    Abstract

    An inert hydrophobic buoyant coated core was developed as Floating Drug Delivery System (FDDS) for sustained release of cisapride using direct compression technology. Core contained low density, porous ethyl cellulose, which was coated with an impermeable, insoluble hydrophobic coating polymer such as rosin. It was further seal coated with low viscosity hydroxypropyl methyl cellulose (HPMC E15) to minimize moisture permeation and better adhesion with an outer drug layer. It was found that stable buoyant core was sufficient to float... Read More»