Clinical Pharmacology and Therapeutics Unit, Department of Medicine, University of Benin Teaching Hospital, Benin- city, Nigeria
Frequency and Patterns of Adverse Drug Reactions among Elderly
In-Patients in a Nigerian Teaching Hospital.
Author(s): Paul O Nwani* and Ambrose O Isah
Background: Adverse drug reactions (ADRs) are common and important causes of morbidity and death in the elderly. Though the world elderly population is on a rise, data on the profile of adverse drug reactions (ADR) in Sub-Saharan Africa is still sparse. This study was aimed at determining the frequency of occurrence and patterns of ADR among admitted older Nigerians. Methods: This was a prospective study of patients aged 65 years and above admitted in a Nigerian tertiary health institute. ADR was defined using the World Health Organization (WHO) definition of ADR, while intensive event recording was used to detect ADR. Patients were grouped into those admitted with an adverse drug reaction (ADRad) and those that developed an adverse drug reaction during hospitalization (ADRin). Results: A total of 345 pati.. Read More»