Recommended Conferences

Global Conference on Pharma and Pharmaceutical Sciences

Toronto, Canada

International Conference on Clinical Pharmacy

London, UK

Global Meet on Pharmaceutical Sciences

Zurich, Switzerland

Antibacterial activity of Momordica charantia (Curcubitaceae) extracts and fractions

Author(s): José Galberto M Costa, Eidla M. M. Nascimento, Adriana R Campos, Fabiola F. G. Rodrigues

Momordica charantia L. belongs to the family Curcubitaceae and it is very common in many Brazilian regions. The plant is a liana with flowers and yellow fruits that present red seeds when are ripe. Popularly known as “melão-de-são-caetano”, “melão amargo” or “cabaço-amargo”, it possesses many uses: antidiabetic, antihelmintic, antmicrobial, anticancerigenous and antioxidant. The phytochemical prospection of the fresh and dried leaves extracts showed the presence of different classes of secondary metabolites, as flavonoids, alkaloids and tannins, that have dem-onstrated antimicrobial action. Fresh and dried leaves presented significantly anti-microbial activity against all bacterial strains tested, specially Escherichia coli. Ethyl acetate fractions were effective against Escherichia coli and Bacillus cereus. The mod-ulatory activity was significative too.

Full-Text | PDF