Department of Pharmaceutics and Pharmaceutical Technology, L. M. College of Pharmacy, Navrangpura, Ahmedabad, Gujarat, India


  • Research Article   
    Formulation Development and Evaluation of Vancomycin HCL Nanoparticles for the Treatment of Bacterial Meningitis
    Author(s): Mansi Athalye* and Anuj Patel


    The drugs which are used for the treatment of are bacterial meningitis are ampicillin, gentamycin, cefotaxime, and vancomycin HCL, where vancomycin HCL is broad spectrum antibiotic. There are various Nano particulate drug delivery systems such as dendrimers, lipoic nanoparticles, inorganic nanoparticles and polymeric nanoparticles capable of incorporating the therapeutic drugs or imaging agents with the effective drug targeting at required site in the body. The effective treatment and diagnosis of various CNS diseases is restricted by Blood–Brain Barrier (BBB) which inhibits almost all the macromolecular drugs as well as small-molecule drugs to permeate through brain. The direct drug delivery of drugs to brain may indicate higher therapeutic activity to toxicity ratio as that of systemic drug delivery. The intranasal drug delivery is the noninvasive.. Read More»