Department of Pharmacology, Sree Sai Dental College and Research Center, Srikakulam, India

Publications

  • Case Studies   
    Chronic myeloid leukemia with intense thrombocytosis: A case study
    Author(s): K Laksmi Surekha*, P Pavan kumar and Ganesh Kumar

    Abstract

    A case report of Chronic Myeloid Leukemia (CML) with extreme thrombocytosis. A premenopausal women with an age of 45-year-old was admitted with chief complaints of fatigue and generalized body weakness, upper abdominal pain and two episodes of recent gum bleeds without fever or other bleeding manifestations. No other comorbidities. On Examination of US Abdomen gross splenomegaly and mild hepatomegaly are observed. On investigation, patient was also observed with extreme thrombocytosis (10,500,000/mm3 ) and leuk ocytosis with moderate anemia. By the above investigation of leukocytosis, patient was investigated for CML and found to be positive for BCR-ABL by Reverse Transcription PCR (RT-PCR). And prescribed with imatinib 400 mg/day and achieved a complete hematological response by the end of 3 months. On evaluation, patient responded well to imatin.. Read More»