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Synthesis of Some New 3-Coumarinoyl Pyridinium and Quinolinium Bromides for their Antimicrobial Activity

Author(s): Brajesh Porwal, BS Jayashree, Mahesh Attimarad

3-Bromo acetyl coumarins (4a-c) on treatment with methyl and ethyl es- ters of nicotinic acid, isonicotinic acid (5a-d) gave 3-coumrinoyl pyridinium bromides (7a-l) and with quinoline (6) gave 3-coumarinoyl quinolinium bromides (8a-c). the structures of the final compounds were established by their spectral data. the antimi- crobial activitiy of all the newly synthesized test compounds were evaluated and some of them, showed good antibacterial activity.


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