Author(s): Metwali H, Hasan H, Yousuf M
Pregabalin is now being frequently used to treat many medical conditions such
as fibromyalgia, diabetic peripheral neuropathy, post herpetic neuralgia and as
adjunctive therapy for seizure. Hyponatremia is the most frequent electrolyte
abnormality seen in hospitalized patients. And, Syndrome of Inappropriate
Anti-diuretic Hormone Secretion (SIADH) is a common cause of euvolemic
hyponatremia. Despite Hyponatremia, SIADH and use of Pregabalin being
common in clinical practice, there are only a few case reports of Pregabalin
induced SIADH causing hyponatremia which are reported in our literature. The
aim of this case report is to add to the existing reports about the incidence of
hyponatremia due to pregabalin which will alert the prescriber to monitor serum
sodium levels and identify the cause of hyponatremia in patients newly started
on pregabalin.
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