New-Onset Diabetes after Transplant (NODAT)

Author(s): Vaishnavi L R, Dhanya Dharman, Shaiju S Dharan

New onset diabetes mellitus after transplantation (NODAT) is a well-known complication following solid organ transplantation and has been reported to occur in 4% to 25% of renal transplant recipients, 2.5% to 25% of liver transplant recipients, hepatitis C virus (HCV) infection between 40% and 60% and 2% to 53% of all solid organ transplants. This variation in the reported incidence may be because of lack of a universal agreement on the definition of NODAT, the duration of follow-up, and the presence of modifiable and non-modifiable risks factors. Moreover, reduced patient survival and accelerated graft loss have been reported with NODAT.