Clinical pharmacy services form an essential part of healthcare in secondary care settings. Although still in its infancy in Kuwait, clinical pharmacy have developed dramatically over the past 10 to 15 years. We conducted a descriptive evaluation over a period of 5 months to assess the nature and impact of clinical pharmacy services in a semi-government hospital in Kuwait. Successful interventions during the study period were 590 in medical, cardiology and intensive care units and wards. Clinical pharmacy led to a substantial change in pharmacy profession from a drug-oriented to a more patient-centered approach. It is the area of pharmacy that focuses on the science and practice of rational medication use, as defined by The American College of Clinical Pharmacy.