Pterospermum acerifolium, a widely known plant in Indian drugs possesses numerous therapeutic properties as well as healing properties and protein induction. Acerifolium extract, rate of epithelisation with a rise in wound contraction was determined. Animals tropically treated with 100 present P. acerifolium extract in jelly, the wound healing method was determined quicker as compared to manage cluster that were treated with jelly alone. a major accelerated healing was detected in animals that were to boot prefer with 250mg/kg weight of ethanol P. acerifolium extract daily for twenty consecutive days in conjunction with the topical application 100 present P. acerifolium extract. Throughout wound healing section level was found to be up regulated by P. Acerifolium treatment. Early wound healing could also be pronounced thanks to P. acerifolium extract elevating TNF−α production..