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Global Meet on Pharmaceutical Sciences

Zurich, Switzerland

Cold agglutinin disease in sepsis: A rare entity

Author(s): Ravinder Garg, Neetu Kukar, Sukhminder Jit Singh Bajwa, Shaminder Kaur

Cold agglutinin disease (CAgD) is a type of autoimmune hemolytic anemia which generally occurs in adults and is characterized by the presence of IgM antibodies directed against polysaccharide antigens on red blood cell surface. A 16‑year‑old male, having clinical picture of sepsis and anemia, presented to the Emergency Department of our Institute in an Hemodynamically unstable condition. Investigation profile revealed hemolysis due to CAgD, which responded to corticosteroids, antibiotics and supportive treatment. This case highlights the importance of recognizing this entity in such type of cases presenting with sepsis and anemia.


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