Cardiovascular Disease in Chronic Kidney Disease Patients: A Review

Author(s): Olutoyin M Lawal*, Oluseyi A Adejumo and Adenike C Enikuomehin

The link between Chronic Kidney Disease (CKD) and Cardio Vascular Disease (CVD) has long been established. This association was first suggested by Richard Bright in the early 19th century and has been substantiated in the intervening years. However, the subject has been gaining more attention in recent years. CKD has been termed cardiovascular risk equivalent, hence CKD is an independent risk factor for CVD. CVD is higher in CKD patients compared with the general population, the higher the CKD stage, the higher the CVD risk. CVD has been found to be the major cause of mortality and significant contributor to morbidity in CKD patients and it enhances the rapidity of progression of CKD in such patients. CKD patients are more likely to succumb to CVD than the CKD itself.In spite of these well-established facts, the prevention, diagnosis and treatment of cardiovascular disease in CKD are fought with various controversies. Many studies have shown that correction for the risk factors (both traditional and novel) did not counteract the effect of CKD on CVD risk.

Full-Text | PDF