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Citations : 14978

Journal of Basic and Clinical Pharmacy received 14978 citations as per google scholar report

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Carbamazepine-induced angioedema.

Author(s): Ansha Subramanian, Mangaiarkkarasi Adhimoolam, Senthil Gopalakrishnan, Meher Ali Rajamohammed

Angioedema is a rare adverse reaction of carbamazepine, which causes localized tissue edema in submucosal and subcutaneous tissue mediated by histamine, serotonin, and kinins (bradykinin). We report a case of 34â�?�?�?�?yearâ�?�?�?�?old female who developed angioedema, 24 h after administration of carbamazepine for treating bipolar disorder. Patient’s symptoms responded rapidly with antihistamine therapy and with the withdrawal of carbamazepine, the offending drug. Carbamazepineâ�?�?�?�?induced angioedema is a lifeâ�?�?�?�?threatening reaction which requires immediate treatment and monitoring in order to avoid morbidity and mortality.

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