+44-7482878454

Recommended Conferences

Global Meet on Pharmaceutical Sciences

Zurich, Switzerland

Carbamazepine-induced angioedema.

Author(s): Ansha Subramanian, Mangaiarkkarasi Adhimoolam, Senthil Gopalakrishnan, Meher Ali Rajamohammed

Angioedema is a rare adverse reaction of carbamazepine, which causes localized tissue edema in submucosal and subcutaneous tissue mediated by histamine, serotonin, and kinins (bradykinin). We report a case of 34‑year‑old female who developed angioedema, 24 h after administration of carbamazepine for treating bipolar disorder. Patient’s symptoms responded rapidly with antihistamine therapy and with the withdrawal of carbamazepine, the offending drug. Carbamazepine‑induced angioedema is a life‑threatening reaction which requires immediate treatment and monitoring in order to avoid morbidity and mortality.


Full-Text | PDF