A Comprehensive Analysis of Impact of Past Medications on Current Admission in a Tertiary Care Hospital: A Prospective Observational Study

Author(s): Anusha Nukala, Harshika Vanga, Krishnaveni Kandukuri, Thatikonda Keerthi*, Shaik Mohammed Sumeer and Venkateswarlu Konuru

Background: Drug-Related Problems (DRPs) account for $76.6 billion in hospital costs, 8.7 million hospital admissions, and 17 million emergency room visits annually. Identification and resolution of DRPs predominantly help to achieve better therapeutic outcomes and improved patient care.

Objective: The study aimed to analyse the impact of past medications on current admission in a tertiary care hospital.

Methods: A hospital-based prospective observational study was conducted over a period of six months from October 2019 to March 2020. The necessary data was collected from in-patient case notes, past treatment charts, interviews with patients or patient caregivers and nursing staff. The collected data were analysed using Microsoft Excel 2010 and DRPs were classified based on Hepler and Strand classification and assessed its severity.

Results: A total of 210 patient case sheets were reviewed during the study period. Out of which 75 patients had DRPs, on average of 1 DRP per patient were identified. The most common DRP was adverse drug reaction 66 (88%), drug without indication 5 (6.6%), and sub-therapeutic dosage 2 (2.6%). The majority level of significance of DRPs was seen to have mild 39 (52%), moderate 30 (40%), and severe 6 (8%) impact.

Conclusion: Our present study focuses that adverse drug reaction is the most commonly occurring DRP faced by the patients as an aftereffect of their past medication usage followed by drug use without indication. DRPs that result in hospital admission though most of them are avoidable with little vigilant effort.

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